[Dec 14, 2021] Free Board of Pharmacy Specialties BPS-Pharmacotherapy Official Cert Guide PDF Download
BPS BPS-Pharmacotherapy Official Cert Guide PDF
NEW QUESTION 86
A patient is admitted to the hospital after a motor vehicle collision. The patient takes methadone
40 mg once daily for management of an opiate addiction. The remainder of the patient's medical history is unremarkable. The medical resident caring for the patient wants to order methadone but Expresses concern related to the Substance Abuse and Mental Health Services Administration (SAMHSA) regulations.
What is the appropriate action?
- A. Order methadone 40 mg once daily if the medical resident is a registered opioid treatment program (OTP) practitioner.
- B. Order morphine at equivalent dose as an alternative management.
- C. Order methadone 40 mg once daily during inpatient treatment.
- D. Order methadone 40 mg once daily if the patient shows signs of withdrawal.
Answer: C
NEW QUESTION 87
A new team has been established in a large healthcare system to conduct research. At the first meeting of the new team, the pharmacotherapy specialist was asked to submit a proposal for a randomized clinical study. What is the first step in formulating the research hypothesis for this proposal?
- A. Formulating an answerable question
- B. Selecting a viable intervention
- C. Selecting an appropriate comparator
- D. Determining a measurable outcome
Answer: A
NEW QUESTION 88
Which is the most effective method to improve the safety of the use of phytonadione in an institution with a 24-hour pharmacy?
- A. Establishment of emergency preparedness kits containing phytonadione to be stored in the patient care areas where warfarin is used
- B. Removal of phytonadione from all patient care areas of the facility coupled with strict usage guidelines
- C. Computer order sets that default to using a standardized number of vials or amps of phytonadione per dose
- D. Yearly in-service education and medical staff presentation about phytonadione use
Answer: B
NEW QUESTION 89
A 25-year-old man who weighs 80 kg is brought to the emergency department following a motor vehicle collision. He has severe facial contusions and a presumed closed head injury. His Glasgow Coma Scale score is 8. An emergency CT scan shows no evidence of intracranial bleeding. What should recommendations for therapy include?
- A. Phenytoin 1,200 mg intravenously over 45 minutes, then an appropriate maintenance dose for one week
- B. Dexamethasone 10 mg intravenously q6h for one week
- C. Diazepam 5 mg intravenously over 5 minutes, qh6 for one week
- D. Fosphenytoin 25 PE/kg intravenous push, then an appropriate maintenance dose for one week
Answer: B
NEW QUESTION 90
A 14-year-old boy has mild papulopustular acne on the forehead, the nose, and the cheeks, with sparse involvement of the upper trunk and the neck. Which of the following is the most appropriate initial therapeutic agent?
- A. Oral tretinoin
- B. Topical erythromycin
- C. Topical benzoyl peroxide
- D. Topical isotretinoin
Answer: D
NEW QUESTION 91
A 53-year-old patient is admitted to the hospital with diarrhea. He has been experiencing five unformed stools daily for 2 days. The patient had a previous admission 6 weeks ago for C.
difficile diarrhea, which was treated successfully with oral metronidazole. Stool tests are again positive for C. difficile toxin A.
On presentation, his vital signs are: BP 128/86 mm Hg, HR 75 bpm, RR 14 bpm, and T37.8°C.
WBC count shows 12,300 cells/ul (80% neutrophils-segs, 10% neutrophils-bands), serum creatinine 1.2 mg/dL, and albumin 3.4 g/dL. The patient has no evidence of colitis, toxic megacolon, or perforation on imaging studies of the abdomen.
What is the most appropriate treatment recommendation for this patient?
- A. Vancomycin 125mg orally four times daily
- B. Rifaximin 550mg orally three times daily
- C. Metronidazole 500mg orally three times daily
- D. Vancomycin 125 mg orally four times daily plus metronidazole 500 mg three times daily intravenously
Answer: C
NEW QUESTION 92
A 54-year-old male patient (BSA = 1.8 m2) is being treated for head and neck cancer with the following regimen:
* Cisplatin 100 mg/m2 intravenously on day 1
* 5-Fluorouracil 1000 mg/m2 intravenously by continuous infusion on days 1 through 5
* Ondansetron 16 mg intravenously
Which of the following is the appropriate administration instruction for ondansetron?
- A. Daily prior to 5-fluorouracil infusion on days 1 through 5
- B. Thirty minutes before Cisplatin on day 1
- C. Thirty minutes prior to Cisplatin, thereafter as needed for nausea
- D. One dose 30 minutes before Cisplatin and a repeat dose immediately before 5- fluorouracil on day 1; then repeat daily before 5-fluorouracil
Answer: B
NEW QUESTION 93
A 45-year-old patient develops neutropenia, fever, headache, meningismus, and lethargy after induction chemotherapy for acute lymphocytic leukemia. A lumbar puncture reveals 1,000 total nucleated cells with elevated CSF protein with gram stain showing Gram-positive rods. Which of the following is the best initial empiric therapy for this patient?
- A. Ampicillin and cefotaxime
- B. Ampicillin
- C. Ceftriaxone
- D. Ceftazidime and gentamicin
Answer: C
NEW QUESTION 94
A pharmacotherapy specialist is contemplating Writing a case report on a suspected penicillin induced neutropenia in a patient who received intravenous penicillin G for treatment of infective endocarditis. The specialist has established a temporal relationship between the period of medication administration and the onset of neutropenia, and has excluded other potential causes of the adverse effect.
Which of the following is the most appropriate next step in composing the case report?
- A. Describe the incidence, severity, and outcome of penicillin-induced neutropenia for the introduction section of the report.
- B. Perform a comprehensive literature search to identify existing literature describing neutropenia in penicillin-treated patients.
- C. Collect all pertinent patient information, including past medical history, laboratory data, medication history, and consent.
- D. Generate ideas and wording for the patient case summary portion of the report.
Answer: B
NEW QUESTION 95
A 55 year old woman being treated for hypothyroidism with levothyroxine 125 mcg daily is currently euthyroid. She now has menopausal symptoms and is receiving conjugated estrogens.
What effect is this most likely to have on her thyroid function tests?
- A. No changes in reverse triiodothyronine uptake
- B. Decreased total T4
- C. Decreased free T4
- D. No changes in TSH
Answer: B
NEW QUESTION 96
Healthcare Failure Mode and Effect Analysis (HFMEA) is described as a:
- A. Quality assurance method for analyzing errors to identify their underlying causes.
- B. Joint Commission-required process for monitoring drug prescribing errors and their consequences.
- C. Proactive risk assessment process to identify and reduce potential errors and their consequences.
- D. System analysis method for detecting the overuse or inappropriate use of selected medications within a health system.
Answer: C
NEW QUESTION 97
A 50-kg 15-year-old female patient presents to the emergency department 6 hours after ingesting 100 ferrous sulfate tablets, each containing 325 mg. A pregnancy test is negative, and flat plate radiography of the abdomen demonstrates many tablets in the stomach and throughout the small intestine. The patient is intermittently vomiting, with no tablets recovered in the emesis. The patient is otherwise asymptomatic and stable. Which of the following forms of gastrointestinal decontamination should be recommended?
- A. Whole bowel irrigation
- B. Activated charcoal administration
- C. Gastric lavage
- D. Ipecac syrup administration
Answer: A
NEW QUESTION 98
A 50-year-old woman experienced acute renal failure after receiving contrast dye for an imaging study. Her estimated creatinine clearance is now 20 mL/min. Her medications include:
* Piperacillin/tazobactam 4.5g intravenously every 8 hours
* Azithromycin 500 mg intravenously daily
* Famotidine 40 mg orally twice daily
* Enoxaparin 40 mg subcutaneously daily
* Metoprolol succinate 100 mg orally daily
Which drugs require dose reduction due to acute renal failure?
- A. Piperacillin/tazobactam, famotidine, and enoxaparin
- B. All of her current medications
- C. Piperacillin/tazobactam, azithromycin, and enoxaparin
- D. Piperacillin/tazobactam, famotidine, and metoprolol succinate
Answer: A
NEW QUESTION 99
Administration of a marketed drug to a patient for an off-label indication without approval from a local IRB is permissible in which of the following situations?
- A. The patient's physician has filed a Notice of Claimed Investigational Exemption for a New Drug with the FDA.
- B. The patient's physician considers that the risk/benefit ratio favors the use of the drug.
- C. The drug is administered on the request of the patient or the patient's representative.
- D. The drug is administered under a protocol sponsored by an NIH grant.
Answer: B
NEW QUESTION 100
Investigators studying the relative nephrotoxicity of two aminoglycosides selected their sample size to detect a reduction in toxicity of 10%. Which of the following is the power of this study if the probability of falsely rejecting the null hypothesis is 0.05 and the probability of falsely accepting the null hypothesis is 0.20?
- A. 0.95
- B. 0.05
- C. 0.80
- D. 0.10
Answer: C
NEW QUESTION 101
A 49-year-old patient has been taking pregabalin for the treatment of fibromyalgia for one year with good relief of symptoms. However, this patient recently lost access to health insurance.
Although she experienced excellent relief from pregabalin, she is unable to continue this therapy due to cost.
Which of the following would be the best intervention?
- A. Change to gabapentin
- B. Change to amitriptyline
- C. Change to duloxetine
- D. Change to tramaddy
Answer: C
NEW QUESTION 102
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